diff --git a/src/mainboard/google/rex/Kconfig b/src/mainboard/google/rex/Kconfig
index c10f3f3e14..1d7652c0b3 100644
--- a/src/mainboard/google/rex/Kconfig
+++ b/src/mainboard/google/rex/Kconfig
@@ -4,7 +4,9 @@ config BOARD_GOOGLE_REX_COMMON
 	select EC_GOOGLE_CHROMEEC_BOARDID
 	select HAVE_ACPI_RESUME
 	select HAVE_ACPI_TABLES
+	select I2C_TPM
 	select INTEL_LPSS_UART_FOR_CONSOLE
+	select MAINBOARD_HAS_TPM2
 
 config BOARD_GOOGLE_BASEBOARD_REX
 	def_bool n
@@ -15,6 +17,8 @@ config BOARD_GOOGLE_BASEBOARD_REX
 	select MEMORY_SOLDERDOWN
 	select SOC_INTEL_METEORLAKE
 	select SYSTEM_TYPE_LAPTOP
+	select TI50_FIRMWARE_VERSION_NOT_SUPPORTED
+	select TPM_GOOGLE_TI50
 
 config BOARD_GOOGLE_REX0
 	select BOARD_GOOGLE_BASEBOARD_REX
@@ -62,4 +66,16 @@ config UART_FOR_CONSOLE
 config OVERRIDE_DEVICETREE
 	default "variants/\$(CONFIG_VARIANT_DIR)/overridetree.cb"
 
+config DRIVER_TPM_I2C_BUS
+	hex
+	default 0x4 if BOARD_GOOGLE_REX0
+
+config DRIVER_TPM_I2C_ADDR
+	hex
+	default 0x50
+
+config TPM_TIS_ACPI_INTERRUPT
+	int
+	default 35  # GPE0_DW1_03 (GPP_E03)
+
 endif # BOARD_GOOGLE_REX_COMMON
diff --git a/src/mainboard/google/rex/chromeos.fmd b/src/mainboard/google/rex/chromeos.fmd
index 334cddaf7b..1714e80578 100644
--- a/src/mainboard/google/rex/chromeos.fmd
+++ b/src/mainboard/google/rex/chromeos.fmd
@@ -43,6 +43,7 @@ FLASH 32M {
 		# memory protected range specification.
 		WP_RO 8M {
 			RO_VPD(PRESERVE) 16K
+			RO_GSCVD 8K
 			RO_SECTION {
 				FMAP 2K
 				RO_FRID 64
diff --git a/src/mainboard/google/rex/variants/rex0/overridetree.cb b/src/mainboard/google/rex/variants/rex0/overridetree.cb
index 65c1c81671..f5d9430b22 100644
--- a/src/mainboard/google/rex/variants/rex0/overridetree.cb
+++ b/src/mainboard/google/rex/variants/rex0/overridetree.cb
@@ -110,7 +110,13 @@ chip soc/intel/meteorlake
 		device ref i2c2 on end
 		device ref i2c3 on end
 		device ref sata on end
-		device ref i2c4 on end
+		device ref i2c4 on
+			chip drivers/i2c/tpm
+				register "hid" = ""GOOG0005""
+				register "irq" = "ACPI_IRQ_EDGE_LOW(GPP_E03_IRQ)"
+				device i2c 50 on end
+			end
+		end
 		device ref i2c5 on end
 		device ref pcie_rp5 on
 			# Enable WLAN Card PCIE 5 using clk 5